ⓘ Bladder sphincter dyssynergia and neurogenic detrusor overactivity is a consequence of a neurological pathology such as spinal injury or multiple sclerosis. whi ..

                                     

ⓘ Bladder sphincter dyssynergia

Bladder sphincter dyssynergia and neurogenic detrusor overactivity) is a consequence of a neurological pathology such as spinal injury or multiple sclerosis. which disrupts central nervous system regulation of the micturition reflex resulting in dyscoordination of the detrusor muscles of the bladder and the male or female external urethral sphincter muscles. In normal lower urinary tract function, these two separate muscle structures act in synergistic coordination. But in this neurogenic disorder, the urethral sphincter muscle, instead of relaxing completely during voiding, dyssynergically contracts causing the flow to be interrupted and the bladder pressure to rise.

                                     

1. Presentation

People with this condition generally experience daytime and night time wetting, urinary retention, and often have a history of urinary tract and bladder infections. Constipation and encopresis are often associated with this condition.

                                     

2. Pathology

The pathophysiology of the condition results from neuronal plasticity associated with bladder afferents and motor neurons innervating the external urethral sphincter.

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