ⓘ Drosophila melanogaster genes ..

Achaete-scute complex

The achaete-scute complex is a group of four genes in the fruit fly Drosophila melanogaster. These genes encode basic helix-loop-helix transcription factors that have been best studied in their regulation of nervous system development. Because of their role in specifying neuroblast fate, the genes of the AS-C are called proneural genes. However, the AS-C has non-proneural functions, such as specifying muscle and gut progenitors. Homologues of AS-C in other animals, including humans and other vertebrates, have similar functions. Genes of the AS-C interact with the Notch pathway in both thei ...

Amnesiac gene

By suppressing dunce through mutagenesis, the amnesiac gene plays a role in reproduction of Drosophila because dunce is the sterility gene. This molecule has similar peptides to pituitary adenylyl cyclase-activating peptide PACAP and growth hormone-releasing hormone GHRH. The biological role of amnesiac gene is activating the adenyl cyclase second messenger pathway cAMP involved in its memory retrieval through these two peptides. The sensory and motor capabilities of amnesiac are normal, but it is memory retrieval that is affected, not storage. The amnesiac gene is directly involved in dev ...


Antennapedia is a Hox gene first discovered in Drosophila which controls the formation of legs during development. Loss-of-function mutations in the regulatory region of this gene result in the development of the second leg pair into ectopic antennae. By contrast gain-of-function alleles convert antennae into ectopic legs. This is just one illustration of the tendency of organisms to exhibit variations on a theme, modulated repetition. Legs and antennae are related to one another as much as molars are to incisors, fingers are to toes, and arms are to legs. Antp also refers to a gene comple ...

Bithorax complex

The Bithorax complex is one of two Drosophila melanogaster homeotic gene complexes, located on the right arm of chromosome 3. It is responsible for the differentiation of the posterior two-thirds of the fly by the regulation of three genes within the complex: Ultrabithorax, abdominal A, and Abdominal B. A complete deletion of this complex results in the posterior segments of the Drosophila embryo becoming copies of the second thoracic segment.

Faint little ball

Faint little ball is a Drosophila gene that encodes the Drosophila epidermal growth factor receptor homolog. The gene is also called torpedo and Ellipse. The gene is located at 3-26 of the Drosophila melanogaster genome. It is named faint little ball because when the gene is mutated the embryo forms a ball of dorsal hypoderm. flb is necessary for several processes to occur during embryonic development, specifically in central nervous system development. It is expressed as quickly as 4 hours after fertilization of the egg. The peak of expression of the flb gene is between 4–8 hours into dev ...


dClock is a gene located on the 3L chromosome of Drosophila melanogaster. Mapping and cloning of the gene indicates that it is the Drosophila homolog of the mouse gene CLOCK. The Jrk mutation disrupts the transcription cycling of per and tim and manifests dominant effects.


Rutabaga (gene)

Rutabaga is the name of the gene encoding calcium-sensitive dependent adenylate cyclase in fruit flies. Rutabaga has been implicated in a number of functions, including learning and memory, behavior, and cell communication. Mutants display defects in olfactory memory, leading to presumably defects in learning to consume rutabaga. Its human homolog is ADCY1.


Spitz (protein)

Spitz is produced as a transmembrane protein in the endoplasmic reticulum. There it associates with a cargo receptor called Star and is trafficked to the Golgi. In the Golgi, Spitz is cleaved by a protease called Rhomboid, which releases Spitz to be trafficked to the cell membrane and released out of the cell. From here it can bind EGFR on the surface of other cells, activating the receptor. Alternatively, Spitz can be bound and inactivated by Argos, inhibiting EGFR activation.

Free and no ads
no need to download or install

Pino - logical board game which is based on tactics and strategy. In general this is a remix of chess, checkers and corners. The game develops imagination, concentration, teaches how to solve tasks, plan their own actions and of course to think logically. It does not matter how much pieces you have, the main thing is how they are placement!

online intellectual game →