ⓘ Ure2 internal ribosome entry site, IRES. In molecular biology, the Ure2 internal ribosome entry site is an RNA element present in the 5 UTR of the mRNA of Ure2. ..

                                     

ⓘ Ure2 internal ribosome entry site (IRES)

In molecular biology, the Ure2 internal ribosome entry site is an RNA element present in the 5 UTR of the mRNA of Ure2. It allows 5 cap- and eIF4E-independent translation of an N-terminally truncated form of Ure2. This truncated form lacks the prion-forming domain. It is a 104 nucleotide region, smaller than most viral IRES elements, which forms a stem-loop structure. EIF2A represses this IRES resulting in an inhibition of translation of the N-terminally truncated Ure2.

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