ⓘ N-acetyllactosaminide 3-alpha-galactosyltransferase. In enzymology, a N-acetyllactosaminide 3-alpha-galactosyltransferase is an enzyme that catalyzes the chemic ..


ⓘ N-acetyllactosaminide 3-alpha-galactosyltransferase

In enzymology, a N-acetyllactosaminide 3-alpha-galactosyltransferase is an enzyme that catalyzes the chemical reaction

UDP-galactose + beta-D-galactosyl-1-> 4-beta-N-acetyl-D-glucosaminyl-R ⇌ {\displaystyle \rightleftharpoons } UDP + alpha-D-galactosyl-1-> 3-beta-D-galactosyl-1-> 4-beta-N- acetylglucosaminyl-R

Thus, the two substrates of this enzyme are UDP-galactose and, and acetylglucosaminyl-R.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-galactose:N-acetyllactosaminide 3-alpha-D-galactosyltransferase. Other names in common use include alpha-galactosyltransferase, UDP-Gal:beta-D-Gal1.4-D-GlcNAc alpha1.3-galactosyltransferase, UDP-Gal:N-acetyllactosaminide alpha1.3-galactosyltransferase, UDP-Gal:N-acetyllactosaminide alpha-1.3-D-galactosyltransferase, UDP-Gal:Galbeta1-> 4GlcNAc-R alpha1-> 3-galactosyltransferase, UDP-galactose-acetyllactosamine alpha-D-galactosyltransferase, UDPgalactose:beta-D-galactosyl-beta-1.4-N-acetyl-D-glucosaminyl-, glycopeptide alpha-1.3-D-galactosyltransferase, glucosaminylglycopeptide alpha-1.3-galactosyltransferase, uridine diphosphogalactose-acetyllactosamine, alpha1-> 3-galactosyltransferase, uridine diphosphogalactose-acetyllactosamine galactosyltransferase, uridine, diphosphogalactose-, galactosylacetylglucosaminylgalactosylglucosylceramide, galactosyltransferase, beta-D-galactosyl-N-acetylglucosaminylglycopeptide, and alpha-1.3-galactosyltransferase. This enzyme participates in 3 metabolic pathways: glycosphingolipid biosynthesis - lactoseries, glycosphingolipid biosynthesis - neo-lactoseries, and glycan structures - biosynthesis 2.

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