ⓘ N-acyl-D-amino-acid deacylase. In enzymology, a N-acyl-D-amino-acid deacylase is an enzyme that catalyzes the chemical reaction N-acyl-D-amino acid + H 2 O ⇌ {\ ..

                                     

ⓘ N-acyl-D-amino-acid deacylase

In enzymology, a N-acyl-D-amino-acid deacylase is an enzyme that catalyzes the chemical reaction

N-acyl-D-amino acid + H 2 O ⇌ {\displaystyle \rightleftharpoons } an acid + D-amino acid

Thus, the two substrates of this enzyme are N-acyl-D-amino acid and H 2 O, whereas its two products are acid and D-amino acid.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-acyl-D-amino acid amidohydrolase. It employs one cofactor, zinc.

                                     

1. Structural studies

As of late 2007, 8 structures have been solved for this class of enzymes, with PDB accession codes 1M7J, 1RJP, 1RJQ, 1RJR, 1RK5, 1RK6, 1V4Y, and 1V51.

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