ⓘ 5-dehydro-4-deoxyglucarate dehydratase. In enzymology, a 5-dehydro-4-deoxyglucarate dehydratase is an enzyme that catalyzes the chemical reaction 5-dehydro-4-de ..

                                     

ⓘ 5-dehydro-4-deoxyglucarate dehydratase

In enzymology, a 5-dehydro-4-deoxyglucarate dehydratase is an enzyme that catalyzes the chemical reaction

5-dehydro-4-deoxy-D-glucarate ⇌ {\displaystyle \rightleftharpoons } 2.5-dioxopentanoate + H 2 O + CO 2

Hence, this enzyme has one substrate, 5-dehydro-4-deoxy-D-glucarate, but three products: 2.5-dioxopentanoate, H 2 O, and CO 2.

                                     

1. Enzyme class

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is 5-dehydro-4-deoxy-D-glucarate hydro-lyase decarboxylating 2.5-dioxopentanoate-forming. Other names in common use include 5-keto-4-deoxy-glucarate dehydratase, deoxyketoglucarate dehydratase, D-4-deoxy-5-ketoglucarate hydro-lyase, and 5-dehydro-4-deoxy-D-glucarate hydro-lyase decarboxylating. This enzyme participates in ascorbate and aldarate metabolism.

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