ⓘ Citramalyl-CoA lyase. In enzymology, a citramalyl-CoA lyase is an enzyme that catalyzes the chemical reaction 3S-citramalyl-CoA ⇌ {\displaystyle \rightleftharpo ..

                                     

ⓘ Citramalyl-CoA lyase

In enzymology, a citramalyl-CoA lyase is an enzyme that catalyzes the chemical reaction

3S-citramalyl-CoA ⇌ {\displaystyle \rightleftharpoons } acetyl-CoA + pyruvate

Hence, this enzyme has one substrate, 3S-citramalyl-CoA, and two products, acetyl-CoA and pyruvate.

This enzyme belongs to the family of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 3S-citramalyl-CoA pyruvate-lyase acetyl-CoA-forming. Other names in common use include citramalyl coenzyme A lyase, +-CMA-CoA lyase, and 3S-citramalyl-CoA pyruvate-lyase. This enzyme participates in pyruvate metabolism and c5-branched dibasic acid metabolism.

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