ⓘ NADPH dehydrogenase, quinone. In enzymology, a NADPH dehydrogenase is an enzyme that catalyzes the chemical reaction NADPH + H + + acceptor ⇌ {\displaystyle \ri ..

                                     

ⓘ NADPH dehydrogenase (quinone)

In enzymology, a NADPH dehydrogenase is an enzyme that catalyzes the chemical reaction

NADPH + H + + acceptor ⇌ {\displaystyle \rightleftharpoons } NADP + + reduced acceptor

The 3 substrates of this enzyme are NADPH, H +, and acceptor, whereas its two products are NADP + and reduced acceptor.

This enzyme belongs to the family of oxidoreductases, specifically those acting on NADH or NADPH with other acceptors. The systematic name of this enzyme class is NADPH:quinone-acceptor oxidoreductase. Other names in common use include reduced nicotinamide adenine dinucleotide phosphate quinone, dehydrogenase, NADPH oxidase, and NADPH2 dehydrogenase quinone. It has 2 cofactors: FAD, and Flavoprotein. Several compounds are known to inhibit this enzyme, including Folate, and Dicumarol.

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