ⓘ 4-hydroxymandelate synthase. In enzymology, a 4-hydroxymandelate synthase is an enzyme that catalyzes the chemical reaction 4-hydroxyphenylpyruvate + O 2 ⇌ {\di ..

                                     

ⓘ 4-hydroxymandelate synthase

In enzymology, a 4-hydroxymandelate synthase is an enzyme that catalyzes the chemical reaction

4-hydroxyphenylpyruvate + O 2 ⇌ {\displaystyle \rightleftharpoons } 4-hydroxymandelate + CO 2

Thus, the two substrates of this enzyme are 4-hydroxyphenylpyruvate and oxygen, whereas its two products are 4-hydroxymandelate and carbon dioxide.

This enzyme belongs to the family of oxidoreductases, specifically those acting on single donors with O 2 as oxidant and incorporation of two atoms of oxygen into the substrate oxygenases. The oxygen incorporated need not be derived from O 2. The systematic name of this enzyme class is 4-hydroxyphenylpyruvate:oxygen oxidoreductase decarboxylating. This enzyme is also called 4-hydroxyphenylpyruvate dioxygenase II.

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