ⓘ Cob II alamin reductase. In enzymology, a cobalamin reductase is an enzyme that catalyzes the chemical reaction 2 cobIalamin + NAD + ⇌ {\displaystyle \rightleft ..

                                     

ⓘ Cob(II)alamin reductase

In enzymology, a cobalamin reductase is an enzyme that catalyzes the chemical reaction

2 cobIalamin + NAD + ⇌ {\displaystyle \rightleftharpoons } 2 cobIIalamin + NADH + H +

Thus, the two substrates of this enzyme are cobIalamin and NAD +, whereas its 3 products are cobIIalamin, NADH, and H +.

This enzyme belongs to the family of oxidoreductases, specifically those oxidizing metal ion with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is cobIalamin:NAD+ oxidoreductase. Other names in common use include vitamin B12r reductase, B12r reductase, and NADH2:cobIIalamin oxidoreductase. This enzyme participates in porphyrin and chlorophyll metabolism. It employs one cofactor, FAD.

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