ⓘ Reticuline oxidase. In enzymology, a reticuline oxidase is an enzyme that catalyzes the chemical reaction S-reticuline + O 2 ⇌ {\displaystyle \rightleftharpoons ..

                                     

ⓘ Reticuline oxidase

In enzymology, a reticuline oxidase is an enzyme that catalyzes the chemical reaction

S-reticuline + O 2 ⇌ {\displaystyle \rightleftharpoons } S-scoulerine + H 2 O 2

Thus, the two substrates of this enzyme are S-reticuline and O 2, whereas its two products are S-scoulerine and H 2 O 2.

This enzyme belongs to the family of oxidoreductases, specifically those acting on X-H and Y-H to form an X-Y bond with oxygen as acceptor. The systematic name of this enzyme class is S-reticuline:oxygen oxidoreductase methylene-bridge-forming. Other names in common use include BBE, berberine bridge enzyme, berberine-bridge-forming enzyme, and tetrahydroprotoberberine synthase. This enzyme participates in alkaloid biosynthesis i.

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