ⓘ MRNA, nucleoside-2-O- -methyltransferase. In enzymology, a mRNA -methyltransferase is an enzyme that catalyzes the chemical reaction S-adenosyl-L-methionine + m ..

                                     

ⓘ MRNA (nucleoside-2-O-)-methyltransferase

In enzymology, a mRNA -methyltransferase is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + m 7 G5pppR-RNA ⇌ {\displaystyle \rightleftharpoons } S-adenosyl-L-homocysteine + m 7 G5pppRm-mRNA containing a 2-O-methylpurine cap

Thus, the two substrates of this enzyme are S-adenosyl methionine and m7G5pppR-RNA, whereas its two products are S-adenosylhomocysteine and m7G5pppRm-mRNA containing a 2-O-methylpurine cap.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:mRNA nucleoside-2-O--methyltransferase. Other names in common use include messenger ribonucleate nucleoside 2-methyltransferase, and messenger RNA nucleoside-2--methyltransferase.

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