ⓘ 6-pyruvoyltetrahydropterin 2-reductase. In enzymology, a 6-pyruvoyltetrahydropterin 2-reductase is an enzyme that catalyzes the chemical reaction 6-lactoyl-5.6. ..

                                     

ⓘ 6-pyruvoyltetrahydropterin 2-reductase

In enzymology, a 6-pyruvoyltetrahydropterin 2-reductase is an enzyme that catalyzes the chemical reaction

6-lactoyl-5.6.7.8-tetrahydropterin + NADP + ⇌ {\displaystyle \rightleftharpoons } 6-pyruvoyltetrahydropterin + NADPH + H +

Thus, the two substrates of this enzyme are 6-lactoyl-5.6.7.8-tetrahydropterin and NADP +, whereas its 3 products are 6-pyruvoyltetrahydropterin, NADPH, and H +.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD + or NADP + as acceptor. The systematic name of this enzyme class is 6-lactoyl-5.6.7.8-tetrahydropterin:NADP + 2-oxidoreductase. Other names in common use include 6-pyruvoyltetrahydropterin reductase, 6PPH42-oxo reductase, 6-pyruvoyl tetrahydropterin 2-oxoreductase, 6-pyruvoyl-tetrahydropterin 2-reductase, and pyruvoyl-tetrahydropterin reductase. This enzyme participates in folate biosynthesis.

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