ⓘ Sn-glycerol-1-phosphate dehydrogenase. In enzymology, a sn -glycerol-1-phosphate dehydrogenase is an enzyme that catalyzes the chemical reaction sn-glycerol 1-p ..

                                     

ⓘ Sn-glycerol-1-phosphate dehydrogenase

In enzymology, a sn -glycerol-1-phosphate dehydrogenase is an enzyme that catalyzes the chemical reaction

sn-glycerol 1-phosphate + NADP + ⇌ {\displaystyle \rightleftharpoons } glycerone phosphate + NADPH + H +

The 3 substrates of this enzyme are sn-glycerol 1-phosphate, NAD +, and NADP +, whereas its 4 products are glycerone phosphate, NADH, NADPH, and H +.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD + or NADP + as acceptor. The systematic name of this enzyme class is sn-glycerol-1-phosphate:NADP + 2-oxidoreductase. This enzyme is also called glycerol-1-phosphate dehydrogenase.

G-1-P dehydrogenase is responsible for the formation of sn -glycerol 1-phosphate, the backbone of the membrane phospholipids of Archaea. The gene encoding glycerol-1-phosphate dehydrogenase has been detected in all the archaeal species and has not been found in any bacterial or eukaryal species. sn -glycerol 1-phosphate produced by this enzyme is the most fundamental difference by which Archaea and bacteria are discriminated.

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