ⓘ HLA-B53 is an HLA-B serotype. The serotype identifies the more common HLA-B*53 gene products. The B53 sequence is identical to B35 but short sequence specifies ..

                                     

ⓘ HLA-B53

HLA-B53 is an HLA-B serotype. The serotype identifies the more common HLA-B*53 gene products. The B53 sequence is identical to B35 but short sequence specifies a Bw4 rather than a Bw6 motif, indicating B53 is a recent product of gene conversion. This suggests an origin for HLA-B53 involving a gene conversion of HLA-B35 by an allele containing this Bw4 sequence.